Propolis

Promunel® Organic Propolis — Clinically Studied Bee Immune Defense

Carotec's Promunel propolis is not ordinary bee propolis. It is a certified organic, alcohol-free liquid extract made exclusively from Promunel® — a standardized, clinically studied brown propolis extract produced by B Natural of Italy using a patented Multi Dynamic Extraction (M.E.D.™) process. 

• Each 20-drop serving delivers a precise 12 mg of polyphenols, the active compounds responsible for propolis's well-documented immune and respiratory benefits. 
• Available in a 1-ounce glass bottle with dropper. 
• Organic propolis in organic glycerin. 
• No sugars, no sweeteners, no flavors.

 

What makes Promunel® propolis different from ordinary bee propolis

Raw propolis varies dramatically from hive to hive and season to season. Its chemical composition shifts depending on geographic region, local plant species, and the time of year — making quality control extremely difficult and rendering most commodity propolis extracts inconsistent and poorly characterized.

Promunel® solves this with the patented M.E.D.™ (Multi Dynamic Extraction) process:

• Uses multiple solvent concentrations throughout extraction to capture a broader, more complete range of polyphenols — including flavonoids, phenolic acids, and glycosylated fractions that single-solvent methods miss.
• Standardized to six key bioactive polyphenols: galangin, quercetin, pinocembrin, pinobanksin, apigenin, and chrysin — the compounds with the strongest documented antimicrobial activity.
• 96% of Promunel's polyphenol fingerprint has been fully identified and characterised, enabling clinical-grade reproducibility.
• 72% bioavailability demonstrated — meaning the active polyphenols are efficiently absorbed from the gastrointestinal tract.
• Sourced from carefully screened beekeeping operations, free of pesticides and contaminants, with ethical beekeeping practices that protect colony health.

Clinically studied for upper respiratory and immune support

Promunel® is distinguished from every other propolis supplement on the market by one thing most lack entirely: published clinical evidence on the actual ingredient being sold.

Key findings from clinical studies on Promunel®:

• In a double-blind, randomised, placebo-controlled study of 295 healthy adults, Promunel® reduced the incidence of upper respiratory discomfort events by 29%.
• Promunel® supplementation significantly reduced the risk of experiencing respiratory discomforts by 31%.
• In a separate 122-subject clinical study, 83% of subjects taking Promunel® experienced improvement in upper respiratory tract comfort within 3 days, versus 28% in the placebo group.
• Average duration of respiratory discomfort was shortened by 2 days in the supplemented group.

(These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.)

 

How to take Carotec Promunel® Propolis

• Serving: 20 drops per day, delivering 12 mg of polyphenols. Twenty drops fills approximately ¼ teaspoon.
• How to take it: Take drops directly in your mouth, or mix with honey. If you find the taste too strong, a small amount of Manuka honey almost completely masks the flavour while adding its own complementary benefits.
• Formula: Organic propolis liquid extract (Promunel®) in organic glycerin. No alcohol. No added sugars, sweeteners, or artificial flavours. One 1-ounce glass bottle with dropper.
• Ingredients: Promunel® Organic Liquid Propolis Extract, Organic Glycerin.

Propolis: 5,000 years of use, now standardized

The word propolis comes from the Greek: pro (in front of, or at the entrance to) and polis (community or city) — meaning "before the city" or "in defense of the city." Honeybees produce propolis by combining plant resins, waxes, and their own secretions to seal, sterilize, and protect the hive. Despite having up to 50,000 inhabitants, a humidity of 90%, and an internal temperature of nearly 100°F, a healthy beehive is one of the most sterile environments in nature. Propolis is the hive's immune system.

Ancient Egyptians used propolis in mummification. Hippocrates prescribed it for internal and external disorders. Greek and Roman physicians documented its healing properties. Today, modern extraction science — specifically B Natural's patented M.E.D.™ process — has made it possible to standardize propolis into a clinically reliable ingredient for the first time in its 5,000-year history.

Propolis Frequently Asked Questions

What is Promunel® propolis?

Promunel® is a premium, clinically studied brown propolis extract produced by B Natural of Italy. Unlike commodity propolis — which varies in composition depending on region, season, and bee variety — Promunel® is made using a patented Multi Dynamic Extraction (M.E.D.™) process that produces a standardised, fully characterised extract with a consistent polyphenol profile. 96% of its polyphenol fingerprint is identified, and it is standardised to six specific bioactive compounds: galangin, quercetin, pinocembrin, pinobanksin, apigenin, and chrysin. Carotec's product is an organic liquid extract of Promunel® in organic glycerin.

What does propolis do for the immune system?

Propolis contains a dense concentration of polyphenols — plant-based compounds with demonstrated antioxidant and antimicrobial properties. Research on Promunel® specifically has shown that it supports the body's innate immune readiness through macrophage modulation: it helps reprogram immune cells from a suppressed state towards a more active functional state. In clinical trials, Promunel® supplementation reduced the incidence of upper respiratory discomfort events by 29% and shortened the average duration of respiratory discomfort by approximately 2 days, compared to placebo. Note: these statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

What makes Promunel® propolis different from regular propolis supplements?

Most propolis supplements are made from raw or minimally processed propolis, which has highly variable composition. The six most bioactive polyphenols can be present at very different concentrations from one batch to the next. Promunel® uses the patented M.E.D.™ process to standardise every batch to those same six key polyphenols, meaning the dose and benefit are reproducible. It is also the only propolis with double-blind, placebo-controlled clinical research published in peer-reviewed journals validating its efficacy for upper respiratory tract health. Additionally, Promunel® has 72% demonstrated bioavailability, meaning most of the active polyphenols are successfully absorbed by the body.

What is propolis made of?

Propolis is a resin-like mixture produced by honeybees from plant saps, beeswax, and their own salivary secretions. Bees use it to seal cracks in the hive, reduce vibration, and — most importantly — to sterilize the hive environment. Raw propolis contains over 300 active compounds, including flavonoids, phenolic acids, terpenes, and esters. The composition varies significantly based on geographic region and local plant species. Promunel® uses a proprietary extraction process to identify, concentrate, and standardize the most bioactively important of these compounds into a consistent, clinically reliable extract.

Is Carotec's propolis organic and alcohol-free?

Yes. Carotec's Promunel® Propolis extract is certified organic and uses organic glycerin as the carrier liquid — not alcohol. This is an important distinction: many propolis tinctures use ethanol (alcohol) as a solvent, which some people prefer to avoid. The organic glycerin base also makes it suitable for people who do not consume alcohol for dietary, religious, or personal reasons. There are no added sugars, sweeteners, or artificial flavours.

How much propolis should I take daily?

Carotec recommends 20 drops per day of the Promunel® Propolis liquid extract. This serving delivers 12 mg of polyphenols — consistent with the dosing used in clinical research supporting Promunel's upper respiratory health benefits. Twenty drops fills approximately ¼ teaspoon. You can take it directly in your mouth or mix it with honey. Always consult your healthcare provider before beginning any new supplement, particularly if you have a known allergy to bee products, tree pollen, or balsam of Peru.

Can I be allergic to propolis?

Yes. Propolis can cause allergic reactions in people who are allergic to bees or bee products, tree pollen, or certain balsams and resins. Symptoms can range from mild skin reactions to more serious responses. If you have a known bee allergy or have reacted to bee products in the past, consult your doctor before using propolis. Discontinue use and seek medical advice immediately if you experience any adverse reaction. This product is not suitable for children without paediatric guidance.

Where does Carotec's Promunel® propolis come from?

The propolis used in Carotec's product is sourced from carefully screened beekeeping operations located primarily along the 45th Parallel in Europe, Asia, and the Americas — regions known for biodiversity-rich floral sources that produce high-quality propolis. B Natural, the Italian manufacturer of Promunel®, works under strict contracts with its beekeeping suppliers to ensure sustainable harvesting, healthy colony environments, and freedom from pesticides and contaminants.